New findings in the field of voiding dysfunction, neurourology, and female pelvic health will explore mesh use, botulinum toxin for overactive bladder, new devices and innovations, and nocturia, to name a few topics. Gopal H. Badlani, MD, professor of urology at Wake Forest Baptist Medical Center in Winston-Salem, NC, highlighted the following themes and abstracts in this area.
In studies of sling and mesh use, highlights include trends in use, the effect of the FDA’s warning in a large study (PD05-08), a single institution study showing revival of use, (MP75-02) and a decline in MAUDE registry complaints (PD05-03). A number of papers also deal with revision after removal of a portion or larger piece of mesh (MP75-02) and use of ultrasound in assessing mesh (MP75-08 and MP75-09).
Key abstracts on botulinum toxin discuss its long-term use (PD36-10), repeat injections (PD32-06), cumulative data (MP79-07), sensory aspect on functional MRI (PD04-01), less than ideal outcomes in Parkinson’s disease patients (PD36-01), and its safety in the geriatric population (MP79-08).
“The NIDDK-funded LURN [Lower Urinary Tract Dysfunction Research Network] study continues to generate data on male LUTS clusters (MP79-06), the relationship between post-void residual volume and UTI (MP79-05), and female LUTS clusters (PD50-04),” Dr. Badlani pointed out.
In the area of neuromodulation, key papers include a small study of safe use of lumbosacral MRI in patients with InterStim II (PD50-01), one discussing tined lead removal (MP79-17), and one exploring discontinuation of OAB meds after InterStim placement (MP75-17).
New innovations and devices includes: implantable percutaneous tibial nerve stimulation (MP75-18), use of telemedicine in spinal cord-injured patients (PD04-09), a pilot study of a new drug for stress urinary incontinence (PD05-09), radiofrequency ablation of the trigone (PD32-07), and a new beta-3 agonist for OAB (PD50-03).
Nocturia is a condition that “continues to confound patients and physicians,” Dr. Badlani said. “A lack of correlation with traditionally known causes (MP79-15), prevalence (PD32-03), and a trial of new drugs to treat it (MP79-12 and MP79-13)” are notable topics.