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Dr. Aggarwal on study of androgen annihilation in biochemically relapsed prostate cancer
Rahul Aggarwal, MD, discusses the phase 3 PRESTO trial, which he presented at the 2022 ESMO Congress.
The study found that intensification of androgen-deprivation therapy (ADT) with the addition of the androgen receptor inhibitor apalutamide (Erleada) improved outcomes versus ADT alone in patients with high-risk biochemically relapsed prostate cancer.
The findings also showed, however, that while a third study arm of apalutamide/ADT plus acetate (Zytiga) and prednisone improved outcomes versus ADT alone, there was not a significant additional benefit with this regimen compared with the other experimental arm of just apalutamide/ADT.
Aggarwal is associate professor of Hematology/Oncology, University of California, San Francisco (UCSF), and associate director for Clinical Sciences, UCSF Helen Diller Family Comprehensive Cancer Center.
Blue light cystoscopy decreases risk of recurrence, progression in NMIBC
May 9th 2024“The results of the BRAVO study performed within the VA health care system showed significant decreases in the risk of recurrence and progression, as well as the potential for improved overall survival in patients who received a BLC compared to patients who received WLC only,” says Stephen B. Williams, MD, MBA, MS, FACS, FACHE.
