March 25th 2024
Developed by the AUGS Scientific Committee and Research Agenda Writing Group
February 23rd 2024
Medical Crossfire®: Expert Exchanges to Maximize Clinical Outcomes for Patients with CRPC Through Evidence-Based Personalized Therapy
View More
How the Experts Treat NMIBC During a BCG Shortage—Integrating Recent Approvals and Investigational Therapies
View More
Staying Abreast of the Prostate Cancer Treatment Paradigm From Risk Stratification to Adaptive Sequencing Strategies
View More
Everything You Need to Know About PARP Inhibitor Combinations in Prostate Cancer Care: Why? For Whom? And When?
View More
Clinical Case Vignette Series: Integrating Recent Data into Practice to Improve Outcomes in Advanced Prostate Cancer
View More
Medical Crossfire®: How Will Emerging Data Inform Treatment Planning for Patients With Prostate Cancer in the Community?
View More
Medical Crossfire®: How Does Recent Evidence on PARP Inhibitors and Combinations Inform Treatment Planning for Prostate Cancer Now and In the Future?
View More
Clinicians are ignoring data on HRT and incontinence
May 1st 2006Bethesda, MD-A 2005 study from the large-scale, NIH-sponsoredWomen's Health Initiative (WHI) found that not only does hormonetherapy not relieve urinary incontinence in postmenopausal women,but estrogen (when taken alone) also doubles the risk ofincontinence in women who did not have it before they startedtherapy.
Neural network model helps predict fertility success
May 1st 2006Iowa City, IA-A neural network that takes into accountmaternal age, sperm retrieval technique, type of sperm used, andtype of male factor has been found to be clinically useful forpredicting the outcome of in vitro fertilization/intracytoplasmicsperm injection.
Drug for osteoporosis may benefit prostate cancer patients
April 6th 2006A drug typically used to treat osteoporosis has a potential clinical benefit in treating men with prostate cancer, according to researchers at the Louis Warschaw Prostate Cancer Center at Cedars-Sinai Medical Center, Los Angeles.
Pediatric PUVs may be linked to adult infertility
April 1st 2006Washington--Even after surgical ablation, posterior urethral valves (PUVs) in boys can cause bladder and kidney problems in later years. But now, for the first time, a team of pediatric urologists has shown that PUVs also can affect sex accessory glands and, ultimately, fertility. Justine M. Schober, MD, a pediatric urologist at Hamot Medical Center, Erie, PA, reported the group's findings here at the 2005 American Academy of Pediatrics Section on Urology annual meeting.
Data suggest viral, genetic roles in prostate cancer
April 1st 2006San Francisco--A never-before-seen virus associated with prostate cancer suggests that infection may play a role in the development of the disease in genetically susceptible individuals. The new virus, XMRV, is 25 times more likely to be present in prostate cancer patients with a specific genetic mutation than it is in the general male population, researchers reported at the American Society of Clinical Oncology 2006 Prostate Cancer Symposium here.
Antioxidants are not linked to decreased prostate Ca risk
March 2nd 2006Dietary or supplemental antioxidants do not appear to be associated with a decreased risk of prostate cancer among men in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, suggests a study published last month in the Journal of the National Cancer Institute (2006; 98:245-54).
Psychological therapies may benefit CP/CPPS patients
March 1st 2006Baltimore--Psychological treatment, particularly cognitive behavioral therapy, can help ease chronic pain. That's why these therapies may be able to do the same for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients, argued Judith Turner, PhD, at the NIDDK-sponsored Chronic Pelvic Pain/Chronic Prostatitis Scientific Workshop here.
Genetics could explain chronic pelvic pain
March 1st 2006Baltimore?What causes chronic pain in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)? This could be the wrong question to ask, said Jeffrey S. Mogil, PhD, at the NIDDK-sponsored Chronic Pelvic Pain/Chronic Prostatitis Scientific Workshop. The better question may be: Why do these particular men have chronic pain, whereas others do not?
Clinicians urged to adopt new model of chronic pain
March 1st 2006Baltimore--Scientific thinking about pain in general and chronic pain in particular has changed drastically in the last 50 years. Providers who treat chronic pain syndrome, such as chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), need to discard the old models if they are going to help patients.
Psychological therapies may benefit CP/CPPS patients
March 1st 2006Baltimore--Psychological treatment, particularly cognitive behavioral therapy, can help ease chronic pain. That's why these therapies may be able to do the same for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients, argued Judith Turner, PhD, at the NIDDK-sponsored Chronic Pelvic Pain/Chronic Prostatitis Scientific Workshop here.
Neurophysiologic tests for CP/CPPS show promise
March 1st 2006Baltimore?Someday, you may be using neurophysiologic testing for follow-up and possibly even diagnosis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) before you turn to the four-glass or modified test. That's because, increasingly, CP/CPPS is being recognized not as a disorder of the prostate, but as a neurologic disorder?a chronic pain syndrome that may begin in the viscera, but becomes a nervous system disorder as pain is centralized.
BMI linked with changes that may affect fertility
February 1st 2006Montreal--Men with a body mass index indicative of being overweight or obese may exhibit changes in endocrine levels—notably lower testosterone levels—that could contribute to infertility, new research shows. It is possible, therefore, that fertility problems could be ameliorated with weight loss in some men.
Smoking affects sperm's ability to fertilize
February 1st 2006Montreal--In case your patients need another reason to quit, recent research indicates that smoking tobacco reduces the ability of sperm to fertilize an egg. There appears to be a dose-response relationship, with heavy smokers at greater risk for more severe impairment of sperm, according to a study presented at the American Society for Reproductive Medicine annual meeting here. It remains to be seen whether quitting smoking or even cutting down will lead to improvements in sperm functions that support fertilization.
Nonobstructive azoospermia is tied to genetic defect
February 1st 2006Montreal--Idiopathic, primary nonobstructive azoospermia (NOA) is linked to a genetic defect known as a dysfunctional DNA mismatch repair pathway that also places these men at increased risk for cancer and other medical illnesses. Given that the problem is genetic in origin, the consequences of this defect may be of significance for both patients and their offspring, researchers say. Both concerns require close monitoring by physicians.
Anti-estrogen may benefit some men with idiopathic HH
February 1st 2006Montreal--The anti-estrogen agent clomiphene citrate (Clomid, Milophene, Serophene) may provide an easier, less expensive treatment for infertility among some men with hypogonadotropic hypo-gonadism [HH], according to a small retrospective study. The agent may be worth trying before the more expensive and difficult-to-administer gonadotropins are employed.
Vasectomy reversal: Data point to choice of technique
February 1st 2006Montreal--As the controversy over whether to perform vasovasostomy or vasoepididymostomy for vasectomy reversal rages, two small studies have provided some new insight into when to choose one surgical technique over the other. One study demonstrates that expert surgeons can provide better results with vasoepididymostomy among patients with vasospermia, defined as no sperm in the vasal fluid, regardless of the condition of the vasal fluid. The second study suggests that the presence of sperm parts in the vasal fluid signals that vasovasostomy might be the better option.
Despite drawbacks, TESE-derived sperm is superior
February 1st 2006Montreal--Although testicular sperm extraction (TESE) may provide somewhat better pregnancy rates than the use of ejaculated sperm for intracytoplasmic sperm injection for men with low sperm counts, a higher-than-average proportion of abnormal sperm, or almost no sperm in the ejaculate, TESE does have important disadvantages. It is up to patients and their physicians to choose the appropriate procedure, based on individual circumstances and clinical features, researchers say.
Inhibin B: A better infertility marker than FSH or LH?
February 1st 2006Montreal--The level of inhibin B may be a better marker of male infertility than both the typically used follicle stimulating hormone (FSH) and luteinizing hormone (LH), according to new research. These findings have yet to be confirmed in a large, prospective trial, however.
Gender identity and assignment issues spark debate
February 1st 2006Washington--For children with ambiguous genitalia at birth, surgical techniques have improved vastly, but deciding when and whether to do surgery hasn't gotten easier. That was apparent from the lively and sometimes contentious panel and audience discussion here at the American Academy of Pediatrics Section on Urology annual meeting.
Testis biopsy: Integral to workup of infertile men
February 1st 2006Montreal--Spermatogenesis markers that can be easily obtained from a noninvasive testis biopsy may predict which patients will respond to surgical varicocele repair. Testis biopsy, therefore, should be part of the regular workup for male infertility patients, suggest the authors of the 2005 Society for Male Reproduction and Urology Prize paper presented here at the American Society for Reproductive Medicine annual meeting.