OAB and Incontinence

Chris Du, MD, discusses findings from a study published in Neurourology and Urodynamics.

Acute urinary retention is not uncommon among men who undergo placement of a proprietary transobturator sling (AdVance) for management of postprostatectomy SUI. Still, it is rarely persistent, according to a recent study.

Investigators conducted a systematic literature review and meta-analysis assessing the impact of 3 months or longer anticholinergic use on the risk of multiple subtypes of incident dementia

“Listen. Be emphatic. Be transparent,” Pansy Uberoi, MD, MPH, advises in this interview.

The approval was based on the phase 3 EMPOWUR trial.

Experts in prostate cancer, bladder cancer, kidney stones, OAB/incontinence, BPH, and sexual dysfunction recap all the key advances from 2020.

“Some women described not being told any risks of the surgery… while other women did recall having risks described,” says investigator Pansy Uberoi, MD, MPH.

The findings support continued investigation of the safety and efficacy of mirabegron in men with OAB and concurrent ED, says study author Arthur L. Burnett, II, MD, MBA.

An application for the eCoin device has been submitted to the FDA for regulatory approval.

The FDA is considering an application for vibegron for the treatment of patients with OAB with symptoms of urge urinary incontinence, urgency, and urinary frequency.

The risk of stricture recurrence was higher with endoscopic surgery compared with urethroplasty.

These 5 overactive bladder research papers were recently published in peer-reviewed academic journals.

Investigators observed a median 74% reduction in urinary incontinence episodes at 1 year for women undergoing group-based pelvic floor muscle training compared with a 70% reduction in women undergoing individual PFMT.

"Patients undergoing midurethral sling placement are ideal for postoperative virtual visits," writes Priya Padmanabhan, MD, MPH.

A new trial is exploring whether CLARIX CORD 1K, a cryopreserved umbilical cord allograft, can contribute to a faster return of erectile function and urinary continence after robot-assisted radical prostatectomy.

Investigators reported that the treatment-emergent adverse event results showed combination tamsulosin and mirabegron was well-tolerated and had a favorable safety profile.

The technique also led to better preservation of anatomical structures around the urethra and achieved a low rate of positive surgical margins.

Bilal Chughtai, MD, and Ahra Cho discuss a recent study evaluating the efficacy of dried cranberry powder in women with overactive bladder.

The ELITE study is exploring the InterStim Micro neurostimulator in patients with urinary urge incontinence, urinary frequency, non-obstructive urinary retention, and fecal incontinence.

R. Corey O'Connor, MD, discusses findings from a recent study published in Neurourology and Urodynamics.

Lunan Ji, MD, discusses a recent paper published in Urology that evaluated the quality of patient education materials on YouTube related to overactive bladder.

“Although IPSS may not be familiar to gynecologists and urogynecologists, this minimally invasive self-reported questionnaire is useful in counseling preoperative pelvic organ prolapse patients with OAB symptoms," researchers write.

“The present study clearly shows that test duration and reprogramming during the test phase increases the number of patients that benefit in the long term from sacral neuromodulation,” researchers wrote.

Outcomes for patients using telemedicine were equal, and patients were as satisfied as those who had office-based postoperative visits.

Smoking had a particularly strong impact on OAB risk in younger individuals.

Gopal H. Badlani, MD, discusses the recently presented long-term safety profile of the β-3 adrenoceptor agonist vibegron.

Jeffrey P. Weiss, MD, PhD, discusses how he defines nocturia, how to separate the symptom from overactive bladder, and how he conducts patient work-ups for nocturia

Data from a pivotal trial showed the eCoin Peripheral Neurostimulator led to a clinically significant improvement in urgency urinary incontinence.

Beta 3-adrenergic receptor agonist’s benefits observed at 52 weeks, investigators report.

The OASIS study is examining the RENOVA iStim implantable tibial neuromodulation system for the treatment of women with overactive bladder.