5-ARI, alpha-blocker differ in number of BPH-related complications
May 19th 2011The 5-alpha-reductase inhibitor dutasteride (Avodart) is associated with markedly lower BPH-related complication rates than the alpha-blocker tamsulosin (Flomax), according to a post hoc analysis of two large clinical trials of these agents presented yesterday.
Renal tumors: Salvage ablation successful in half of recurrences
May 18th 2011The recurrence rate following thermal ablation of renal cortical tumors is 6%. About half of recurrences can be managed successfully with salvage ablative procedures, but 20% require extirpative surgery, according to retrospective findings obtained from databases from 10 U.S. centers.
Higher rate of cardiovascular disease seen in men with CP/CPPS
May 18th 2011Men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are associated with a higher rate of arterial stiffness and vascular endothelial dysfunction than those without the condition, say researchers from Cleveland Clinic.
One-fourth of RT patients on ADT experience testosterone breakthrough
May 18th 2011Among men treated with curative radiation therapy and neoadjuvant, adjuvant, or concurrent ADT, about one-fourth fail to achieve or maintain true castrate levels of testosterone suppression, according to a study from the University of British Columbia, Vancouver.
Urethral reconstruction patients show significantly improved QoL, symptom scores
May 17th 2011Patient-reported outcomes after urethral reconstruction reflected improvement in symptomatic and quality of life parameters consistent with objective urodynamic changes, data from a single-center clinical study showed.
PSA paradox: Low levels predict poor prognosis in high-grade PCa
May 17th 2011In men with high-grade prostate cancer, outcomes after radical prostatectomy are generally poorest for those with a low preoperative PSA (<2.5 ng/mL), according to a results of a study investigating disease-specific outcomes.
Agent Orange found linked to kidney cancer
May 16th 2011While Agent Orange, an herbicide used during the Vietnam War, has been previously linked to a variety of types of cancers in Vietnam veterans, new data from the Veterans Affairs Medical Center in Shreveport, LA, indicates that there may be a connection between veterans? in-country exposure and subsequent development of renal cancer.
Pelvic lymph node dissection gives prostate cancer patients good survival outcomes
May 16th 2011Results of a retrospective study investigating men with clinically localized prostate cancer who underwent radical retropubic prostatectomy with bilateral pelvic lymph node dissection (PLND) show a higher than expected incidence of LN metastases, but men with nodal involvement had excellent 10-year clinical recurrence-free survival.
Obesity worsens prognosis for men on early ADT
May 16th 2011Among men receiving early androgen deprivation therapy (ADT) for biochemical recurrence after radical prostatectomy, obesity appears to be a significant risk factor for poorer prognosis, according to the results of a retrospective study presented yesterday.
Traumatic bladder injury may require up-front, aggressive management
May 15th 2011Much of the literature suggests that the majority of extraperitoneal bladder injuries seen in trauma facilities can be managed conservatively. A study from the University of Utah greets that position with a degree of skepticism.
Post-prostate Ca treatment stricture, fistula can be managed successfully
May 15th 2011The urethral strictures and fistulas that sometimes follow localized prostate cancer treatments can be challenging, but skill and experience can often overcome the challenge, according to a study from the University of Colorado Hospital, Aurora, presented yesterday.
Renal stone incidence on the rise among adolescents
May 15th 2011A population-based study evaluating 25-year trends in renal stone findings among children reported a 4% per year increase in incidence, driven largely by consistently escalating renal stone rates in the 12- to 17-year age group, Mayo Clinic researchers reported yesterday.
Short-term outcomes for outpatient procedures unaffected by facility type
May 15th 2011Use of non-hospital ambulatory facilities as the setting for common outpatient urologic procedures does not appear to adversely affect short-term patient morbidity or mortality, according to researchers from the University of Michigan, Ann Arbor.
Conflicting robotic prostatectomy studies underscore robotics debate
May 15th 2011Urologists attending localized prostate cancer sessions at the upcoming AUA annual meeting in Washington will hear more about the ongoing debate on open versus minimally invasive radical prostatectomy, the use of 5-alpha-reductase inhibitors (5-ARIs) in men on active surveillance, and updates on treatment approaches such as high-intensity focused ultrasound.