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Physicians at Vanderbilt University Medical Center, Nashville, have opened a dedicated cardio-oncology service, including urology, medical oncology, radiation oncology, and cardiology.

"What we need most are markers that selectively identify significant cancers, in order to reduce unnecessary biopsies and over-diagnosis," writes Stacy Loeb, MD, MSc.

Two urinary biomarkers for detection of prostate cancer have differing utility in African-American men undergoing prostate biopsy.

New findings from the Johns Hopkins University School of Medicine in Baltimore should be useful to clinicians looking to counsel anxious prostate cancer patients who are undergoing active surveillance.

Four PCa studies presented at the 2015 AUA annual meeting in New Orleans shed some light, with researchers emphasizing the need to optimize screening and to improve treatment selection in older men.

“Both physicians and patients should take into account remaining life expectancy before adopting screening pathways,” a study author says.

The investigational modality was compared with surgical pathology in men undergoing radical prostatectomy.

Urology Times SUO internship program member Brandon Manley, MD, reports on an SUO presentation highlighting several interesting findings on advanced prostate cancer with variant histology.

Researchers hypothesized that during a time of resource scarcity, the incidence of PSA-detected prostate cancer would decrease and the use of noncurative management strategies would increase, reports Urology Times SUO internship program member Ryan Hutchinson, MD.

Analyses of overall survival rates among subgroups of men who received radium-223 dichloride (Ra 223; Xofigo) as part of an expanded access program suggest factors that may have prognostic significance, including effects of prior and concomitant treatments.

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Results of a recently published study examining the safety of the two approaches support stronger consideration for orchiectomy, according to its authors.

Findings of a large study examining histology of newly diagnosed prostate cancer point to concerning trends in the aftermath of the USPSTF’s recommendation against PSA-based screening.

Number of preoperative biopsies does not appear to have any clinically significant effect on self-reported urinary or erectile function outcomes at 1 year after radical prostatectomy, researchers say.

A combination of findings on preoperative multi-parametric magnetic resonance imaging showed good accuracy for predicting lymph node involvement on final pathology in men who underwent robot-assisted radical prostatectomy for prostate cancer, reported researchers from the National Institutes of Health, Bethesda, MD.

"We’re definitely seeing fewer men referred for elevated PSAs," one urologist told Urology Times.

Other pipeline products discussed in this article include an immunotherapy for metastatic bladder cancer, a treatment for lower urinary tract symptoms of BPH, and an investigational clear cell renal cell carcinoma treatment.

Evaluation of online videos is a feasible method for peer review of robot-assisted radical prostatectomy surgical skills, according to a pilot project undertaken by the Michigan Urological Surgery Improvement Collaborative (MUSIC).

Long-term functional outcomes after radical prostatectomy are excellent, regardless of surgical technique, when the procedure is performed by experienced surgeons at a high-volume center, according to a recent study.

Learn more about these products as well as a powered exam table and an app that measures, monitors, and helps improve fertility in men.

The proposed clinical quality measure comes as a pair of JAMA studies note a decline in screening since the USPSTF recommended against screening.

Recent developments in PSA screening point out why policy truly does matter to residents, writes Alan L. Kaplan, MD, in this blog post.

In her first blog post for Urology Times, nurse practitioner Adele M. Caruso, MSN, CRNP, provides an update on the ongoing PSA screening debate and discusses helpful resources to use when questions on screening arise.

Oncologic outcomes are similar using focal cryotherapy and focal high-intensity focused ultrasound for treatment of localized prostate cancer, French urologists reported at the World Congress of Endourology and SWL in London.

Other pipeline products discussed in this article include agents for urinary catheter blockage, prostate cancer, bladder cancer, and overactive bladder.

Findings from a retrospective study lend support to the idea that even in men with a Gleason 7 (3+4) biopsy score, prostate cancer may sometimes act like low-risk disease.

The test could be a step closer to personalized risk-based prostate cancer diagnostic programs, study authors say.

Researchers say they’ve uncovered a wide variation in costs to treat low-risk prostate cancer.

“The best way to avoid overtreatment is to avoid overdiagnosis. MRI allows you to do that," says Mark Emberton, MD.

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