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EPCA-2.19, a second, independent epitope of the EPCA-2 protein, offers extremely high sensitivity and specificity results that are almost identical to those obtained for a first published assay using the EPCA-2.22 epitope.

Tubeless percutaneous nephrolithotomy can be performed safely and effectively without preoperative selection, and it appears to be associated with fewer postoperative intracorporeal changes than standard percutaneous nephrolithotomy.

A gel formulation of oxybutynin for overactive bladder is nearing commercial availability, with the potential for a significant improvement in cosmesis and skin-related side effects.

In the search for novel biomarkers for prostate cancer diagnosis, a urinary assay for prostate cancer gene 3 (PCA3) has emerged as a promising modality.

Evaluating the efficacy of radiofrequency ablation of renal cortical tumors requires a degree of patience because histologic changes and cell death in and near lesions targeted by the treatment may continue to evolve for a year or even longer.

A diagnostic assay based on computer chip technology could allow clinicians-and perhaps patients-to identify urinary tract pathogens in 45 minutes or less and it might also determine antibiotic susceptibility.

Incorporating image guidance into robotic surgery significantly enhanced tumor resection in a series of mock procedures involving surgical phantoms

Minneapolis-Coloplast's Titan inflatable penile prosthetic implant is designed for use in men who have erectile dysfunction as a consequence of nerve damage after prostatectomy and who do not respond to oral ED therapy. The implanted device now features a low-profile pump with inflate/deflate touch pads that move at the patient's control to emulate the look and performance of a natural erection. The One-Touch Release pump is designed to make it easier for patients to learn to operate the device.

An adjustable urethral prosthesis significantly improved urinary symptoms, urine leakage, and quality of life in women with stress urinary incontinence who had failed to improve after prior therapy.

Complications after laparoscopic radical prostatectomy demonstrates the effect of a learning curve and the benefits of improved surgical technique, but shows little difference in overall morbidity when compared with those of anatomic radical retropubic prostatectomy .

In overactive bladder, percutaneous tibial nerve stimulation performs just as well as well as the most frequently prescribed drug.

Tensioning is a challenge in transvaginal tape procedures for stress urinary incontinence.

Two investigational BPH therapies are yielding positive efficacy results in men with the condition, according to studies presented at recent AUA section meetings.

Counting the copies of a specific gene in cells gathered from a urine sample may provide a simple, noninvasive way to detect bladder cancer, according to researchers at The University of Texas M.D. Anderson Cancer Center in Houston.

Among men with nonmetatastic prostate cancer receiving androgen deprivation therapy, once-weekly alendronate (Fosamax) improves bone density and decreases turnover, according to data published in the Journal of Clinical Oncology (2008; 26:4426-34).

Researchers at Fox Chase Cancer Center in Philadelphia have developed a prediction tool that uses a prostate cancer patient's clinical information to estimate the benefit of adding androgen deprivation therapy of various durations to radiation therapy.

A panel of experts convened by AUA has determined that primary cryosurgery is an option for men who have clinically organ-confined prostate cancer of any grade with negative metatastic evaluation. Clinicians using cryosurgery are advised to review this best practice statement, which will be published in the Journal of Urology.

Delayed hemorrhage occurs in less than 2% of the patients following laparoscopic nephrectomy, but that's too few patients to identify any preoperative or perioperative factors that might increase the risks of delayed hemorrhage.

While concerns have been raised about a relationship between shock wave lithotripsy and diabetes or hypertension, data are still lacking.

Stephen Y. Nakada, MD, interviews Jihad Kaouk, MD, about the nuances of single-port surgery technique, patient selection, the learning curve, technical modifications, and outcomes.

Prevalence of symptoms is influenced by adiposity, but in different ways in men and women, suggesting a different pathophysiology of LUTS in men and women.

Results from a series of studies do not confirm prior evidence that extracorporeal shock wave lithtripsy treatment increases the risks of developing diabetes mellitus and hypertension.

This article, the second in a series of three examining medicolegal issues in urology, discusses how the physician should respond to adverse events that affect their patients.

Efforts are under way to make certain urologists' voices are heard when the new Congress convenes in January and considers legislation that will dramatically affect their practices and patients.

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Hypoandrogenism is common among men with nonobstructive azoospermia, and even those with normospermia.

Among infertile men, testicular hypotrophy is about twice as common in men with varicoceles as in those without varicoceles.

Prolonged warm ischemia, increased blood loss, and solitary kidney status predict post-surgical complications.

The AdVance male sling controls mild to moderate urinary incontinence is effective and the functional membranous urethra is lengthened when male sling is in its final position.

When oral antimuscarinic therapy fails for overactive bladder patients who don't leak, intra-detrusor botulinum toxin A (Botox) injection is effective, and costs can be kept down with a lower dose.