Article

Antiseptic lavage after prosthesis removal advised

Shreveport, LA--Antiseptic lavage after removal of a penile prosthesis significantly reduces the risk of infection associated with revision surgery, report the authors of a multicenter study.

Antiseptic lavage of the implant spaces was associated with a 3.17% incidence of infection following implantation of a new prosthesis. In contrast, revision surgery without antiseptic lavage of the implant spaces led to infection in 11.6% of patients, according to Gerard D. Henry, MD, a urologist at Regional Urology in Shreveport, La.

"Revision washout of the implant spaces reduces the infection rate by more than half," Dr. Henry told Urology Times. "The results are fantastic, and the procedure has really caught on among urologists."

Initial results from Dr. Henry's study showed that irrigation of the implant space at the time of revision surgery and implantation of an antibiotic-coated replacement prosthesis lowers the risk of infection during revision surgery for noninfectious reasons (J Urol. 2005; 173:89-92).

A more recent report, presented at the AUA annual meeting, provided data from 3-year follow-up to determine whether the early benefits of antiseptic lavage persisted over time.

Infection rate low

The study involved 232 patients with penile prostheses. The patients had revision surgery for noninfectious reasons at three different institutions between June 2001 and May 2004.

Dr. Henry reported that 189 patients had implant removal followed by antiseptic lavage of their implant spaces before replacement with another inflatable prosthesis. In the remaining 43 patients, an antibiotic-coated device was replaced without antiseptic irrigation of the implant spaces.

To date, infection has occurred in six of 189 patients (3.17%) who had antiseptic irrigation before replacement of the penile prosthesis. In contrast, five of 43 patients (11.6%) developed infections following revision surgery without antiseptic lavage of the implant spaces. The difference between groups was statistically significant (p=.037).

"These results clearly show that revision washout after complete implant removal can markedly decrease the incidence of infection in penile prosthesis patients who undergo revision for noninfectious reasons," said Dr. Henry.

Related Content
Site Logo
March 15th 2007

Seeds vs. prostatectomy: Long- and short-term side effects differ slightly

For men with prostate cancer, radiation seed implants may yield a better short-term side effect profile than surgery, but surgery may offer slightly better long-term outcomes, new research from French radiation oncologists indicates.
Site Logo
February 15th 2007

Brachytherapy offers high 8-year prostate Ca survival rates

More than 90% of men who receive appropriate radiation dose levels with permanent radiation seed implants to treat their prostate cancer are cured of the disease 8 years after diagnosis, according to a recent study in the International Journal for Radiation Oncology Biology Physics (2007; 67:327-33).
Site Logo
February 1st 2007

Research on bladder tissue regeneration progresses

Erinn H. Goldman, PhD
Atlanta-Tissue engineering research has grown by leaps and bounds in the past decade and a half, yielding findings that may someday have a profound impact on the field of pediatric urology. At the 2006 American Academy of Pediatrics Section on Urology annual meeting here, several groups presented cutting-edge data on novel systems for organ generation, including research demonstrating the feasibility of generating a functioning bladder from stem cells.
Site Logo
January 18th 2007

Radiation therapy combination prolongs long-term cure rate in men with PCa

Three-fourths of men treated with a combination of radiation seed implants and external beam radiation therapy for prostate cancer are cured of their disease 15 years following their treatment, according to a study published in the International Journal of Radiation Oncology*Biology*Physics (2007; 67:57-64).
Site Logo
December 7th 2006

Gastric bypass surgery may increase kidney stone risk

Patients who have undergone gastric bypass surgery for morbid obesity have increased risk factors for the formation of kidney stones, according to a study by Mayo Clinic researchers.
Site Logo
October 1st 2006

Cystectomy outcomes: Does surgeon's age matter?

Cheryl Guttman Krader, BS, Pharm
Ann Arbor, MI-Surgeon age is not a significant predictor of risk of mortality after cystectomy, according to the results of a recently published study from researchers at the University of Michigan, Ann Arbor (Ann Surg 2006; 244:353-62).
© 2024 MJH Life Sciences

All rights reserved.