Does BMI affect inflatable penile prosthesis surgery?

In this video, Muhammed A. Moukhtar Hammad, MBBCh, discusses the study “Exploring How BMI Shapes the Success of Inflatable Penile Prosthesis Surgery: Multi-Center Study Insights,” which he presented at the 2024 Sexual Medicine Society of North America Fall Scientific Meeting in Scottsdale, Arizona. Hammad is a Masters of Biomedical and Translational Science Candidate at the University of California, Irvine (UCI) School of Medicine and a clinical research fellow at UCI Health – Department of Urology.

Transcription:

Please provide an overview of this study and its notable findings.

I was presenting this study on behalf of the PUMP collaborative. It's a huge collaborative, international, multi-center study, and we have a big database that we basically extract a lot of ideas from and try to explore. It helps the scientific community, prosthetic urologists, reconstructive urologists, to gain insights from such a huge number of patients. For this project, precisely, we looked at BMI. As you know, obesity is defined by the WHO as greater than or equal to 30 of kilograms per meter squared. Obesity is a prevalent public health concern with far-reaching implications on various medical procedures and outcomes. So we looked basically at whether BMI is going to be of any influence on the post-op, intra-op complications in patients undergoing inflatable penile prosthesis. And when we looked at these results, we tried split the cohort into below 30 BMI and above the 30 threshold, or equal to the 30 threshold, and we had approximately 4000 patients in total. When we split them into the 2 groups, they were actually split nicely into 2000 and 2000. When we did that and we looked at the results, they were striking. These results were reassuring, because basically what we found was, with regards to demographics, we found that there was a statistically significant difference in history of IPP infection and diabetes, of course, more on the above-30 group, which is quite reasonable. But when we [looked at the] complications breakdown, that's where it was really interesting, because we found no overall complication differences between both groups, which is striking, to be honest. Then we looked further into that. We broke them up as much as we could. So you go first, then to interop complications, no statistically significant difference, even urethral injury. I mean, they were slightly higher on the above 30 group, but not statistically significant. But if you compare both groups together, and that's that was really interesting. And then when we went further, to the post-op complications, so including infectious, non infectious complications, again, not significant. But here's the interesting result. Although the rear tip extender usage was not statistically significant between both groups, we found significance in both groups with regards to proximal corporal measurement by around 0.5 cm for the above-30 group, which is quite explainable. A lot of surgeons feel this is quite reassuring as well. And then we wanted to make sure that these results are actually solid through so we adjusted for a lot of covariates, including infection, diabetes, and a bunch of other factors. We tried to make it apples-vs-apples as much as we can, and we found, again, no significant differences in complications. And this is quite reassuring to show that there's no statistically significant influence of BMI in actual complications. However, with these results, we also always say that surgeons should have specific surgical considerations whenever they come to patients with a higher BMI.

This transcript was AI generated and edited by human editors for clarity.