One-third of ICSI procedures in U.S. result in delivery

Nearly one-half of in vitro fertilization cycles are conducted using intracytoplasmic sperm injection. Of those procedures, the delivery rate for IVF using ICSI was 28.8% per retrieval and 30.4% per embryo transfer, according to a study of U.S. data in Fertility and Sterility (2004; 81:1207-20).

Researchers reviewed data collected from 383 programs on assisted reproductive technology performed in 2000. The programs had sent the data to the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry.

Programs reported 99,989 cycles of assisted reproductive technology treatment. Of those, almost three-quarters involved fresh nondonor IVF, with 47% using ICSI.

Established clinical pregnancies with ICSI reached 10,898, with 8,982 deliveries. Over half of the deliveries resulted in one child.

The pregnancy loss rate was 16.5 with IVF/ICSI, and 202 ectopic pregnancies occurred.