Watch for initial findings of pelvic pain research at AUA 2013

This article is part of the State of Urology 2013

At this year’s AUA annual meeting, studies from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network represent the initial drops of an expected “flood of data” in coming years, according to Philip M. Hanno, MD, MPH, of the University of Pennsylvania, Philadelphia.

Two studies from this research endeavor of the National Institute of Diabetes and Digestive and Kidney Diseases being presented in San Diego provide preliminary epidemiologic data, while a third examines the role of microbes in chronic pelvic pain syndromes.

In interstitial cystitis, look for important studies on ileal conduit diversion as an optimal procedure for end-stage bladder pain syndrome (BPS), marker response to neurostimulation in BPS patients that correlates with good study results, and similar efficacy of onabotulinumtoxinA (Botox) in patients with and without Hunner’s lesions.

Here are the abstracts Dr. Hanno says to watch for in the field of chronic pelvic pain/IC:

866: Ileal conduit without cystectomy may be an appropriate option in the treatment of intractable Bladder Pain Syndrome/Interstitial Cystitis

Thomas Norus

869: Treatment Response to Neuromodulation in Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) Patients Accompany Decrease in Urine Chemokines

Michael Chancellor

872: Clinical response to intra-trigonal Onabotulinum toxin A injections is not related to the presence of ulcers in Bladder Pain Syndrome/Interstitial Cystitis patients

Rui Pinto

875: Treatment with a CB2 Agonist Decreases Severity of Established Cystitis

Zunyi Wang

1147: Application of State-of-the-Art Methods to Search for Microbial Contributions to the Etiology of Urological Chronic Pelvic Pain Syndrome (UCPPS)

J. Curtis Nickel

1581: Impact of symptom duration of baseline characteristics of the Multidisciplinary Approach to Pelvic Pain (MAPP) study cohort

Luigi Cormio

1955: Comparison of baseline urologic symptoms in men and women with interstitial cystitis/bladder pain syndrome or chronic prostatitis/chronic pelvic pain syndrome

J. Quentin Clemens

“At this AUA meeting, there are some helpful clinically oriented presentations on IC/BPS that the practicing urologist taking care of these patients will find useful,” Dr. Hanno said. “In addition, reports from the MAPP are starting to be presented. A first look at epidemiologic data generated along with a negative study on microbial influence on BPS etiology are only the beginning of what will become a flood of data in the coming years from this ambitious research effort.”UT