Charles Bankhead

Four-year data on the prostatic urethral lift (UroLift) and data on a new water-jet ablation treatment were among BPH/LUTS highlights from this year’s meeting.

Men with previously treated castration-resistant prostate cancer (CRPC) lived almost 5 months longer when they received the androgen receptor signaling inhibitor enzalutamide.

Repeat surgery occurs two to three times as often after newer minimally invasive interventions for BPH compared with transurethral resection of the prostate.

A robot-assisted laparoscopic radical prostatectomy costs 40% more than a retropubic radical prostatectomy, according to a review of hospital data from one state.

Testosterone replacement therapy (TRT) did not increase the risk of biochemical recurrence in hypogonadal men with localized prostate cancer.

A common variant on chromosome 14 confers a 19% lower risk of bladder cancer, in part because of the variant's association with increased length of telomeres.

Elevated pretreatment androgen levels correlate with significantly better overall survival in men with castration-resistant prostate cancer, regardless of treatment, a recent post hoc analysis of a large randomized trial showed.

Three fourths of patients with refractory urothelial cancer had stable disease or better response when treated with the angiogenesis inhibitor pazopanib (Votrient), Italian researchers recently reported.

Long-term quality of life converges to similarity for prostate cancer patients treated surgically or by radiation therapy, data from a large cohort study show.

Men who took high-dose vitamin D prior to radical prostatectomy had significant reductions in prostate levels of the proliferation marker Ki-67 and increased expression of microRNAs associated with tumor suppression, according to a recent study from Canadian and U.S. researchers.

Patients with nonmuscle-invasive bladder cancer had significantly better recurrence-free survival when treated with the Connaught strain of bacillus Calmette-Gu?rin compared with the Tice strain, according to results of a randomized trial.

Excess body weight correlated with a significantly higher 5-year risk of biochemical recurrence after surgery for clinically localized prostate cancer, according to a study reported at the American Association for Cancer Research annual meeting in Chicago.

The 2012 AUA annual meeting will reflect incremental progress occurring in the management of lower urinary tract symptoms (LUTS) secondary to BPH, as well as emerging information about the epidemiology and underlying biology of the disease process.

Intermittent androgen ablation proved feasible for patients with metastatic prostate cancer, but did not improve survival or quality of life compared with continuous hormonal therapy.

Patients in active surveillance for prostate cancer were almost 20 times more likely to die of causes other than prostate cancer.

Compared with the general population, prostate cancer patients treated with radiation therapy were almost twice as likely to develop rectal cancer.

Erectile dysfunction increased the risk of cardiovascular death by 43% compared with men who had normal erectile function.

Men with low levels of free testosterone had more severe penile curvature, which correlated significantly with free testosterone, according to results of a retrospective chart review.

Cryoablation of small renal masses yields similar survival rates with a laparoscopic or percutaneous approach, but the options involve tradeoffs of disease control versus convenience and cost.

Laparoscopic partial nephrectomy without collection system suturing led to a urine-leak rate comparable to that of procedures with formal collection-system closure.

Brachytherapy and radical prostatectomy are effective treatments for localized prostate cancer, but have different long-term functional effects, 13-year follow-up data show.

Twice-yearly injections of denosumab improved bone mineral density in men with prostate cancer treated with androgen deprivation therapy.

Permanent brachytherapy's long-term success depends on delivery of a high biological effective dose of radiation.

Atlanta-Operating room-based procedures continue to make up a significant proportion of urologists' practice, despite a predominance of office-based clinical practice, data from the American Board of Urology indicate.

Atlanta-Laparoscopic partial nephrectomy (LPN) for solitary and multiple renal tumors led to a small but statistically significant decrease in postoperative renal function, but the clinical significance of the finding remains unclear, according to a retrospective review of a patient series at the National Cancer Institute, Bethesda, MD.

Atlanta-Adjunctive treatment with the alpha-blocker tamsulosin (Flomax) improves stone clearance and significantly reduces ureteral colic following ureteroscopic laser lithotripsy, researchers reported at the AUA annual meeting.

Atlanta-The ability to detect lymph node invasion (LNI) in men undergoing radical prostatectomy relates directly to the extensiveness of pelvic lymph node dissection (PLND), a review of a large clinical series suggests.

Atlanta-The prostate cancer staging benefits of an extensive pelvic lymph node dissection (PLND) come at a price of a significantly increased risk of complications and a significantly longer hospitalization.

San Diego-Treatment with the dual neurotransmitter reuptake inhibitor duloxetine (Yentreve) results in durable improvement in symptoms of stress urinary incontinence, according to a study of open-label transition from placebo to active therapy.

San Diego--Two large studies have arrived at very different conclusions about the value of routine urine cytology and cystoscopy for evaluating women presenting with irritative voiding symptoms.