Mark D. Tyson, II, M.D., M.P.H., explores the current NMIBC landscape, covering risk stratification approaches, established treatments like BCG immunotherapy and TURBT, emerging investigational agents spanning multiple mechanisms of action, and remaining challenges including BCG supply shortages and biomarker development, while highlighting future directions in personalized medicine and novel delivery systems.
EP. 1: Treatment Strategies for Patients with NMIBC: Importance of Risk Stratification
December 19th 2024A panelist discusses how Non-muscle Invasive Bladder Cancer (NMIBC) treatment varies by risk stratification (low, intermediate, and high-risk), with BCG immunotherapy being standard for high-risk patients, while newer options like pembrolizumab and gene therapies are emerging for BCG-unresponsive cases, and treatment decisions between intravesical versus systemic therapy depend on risk level and previous treatment response.