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In this interview, Arie Belldegrun, MD, discusses the benefits of cancer immunotherapy, the importance of a multidisciplinary treatment approach, and what the future holds for this treatment.

Drugs and devices in the pipeline from Actavis, Genomic Health, Lipella Pharmaceuticals, Polaris Group, Innocrin Pharmaceuticals, OncoGenex Pharmaceuticals, Heat Biologics, Repros Therapeutics, and Sophiris Bio.

With emergence of new biomarker and tests, high-profile approvals of treatments for new indication, and the ongoing controversy surrounding PSA screening, prostate cancer remained very much in the urology headlines for 2014. Here are some of the most-read Urology Times articles on the disease.

Streamlined management for metastatic castration-resistant prostate cancer, greater autonomy for residents, and a better understanding of issues facing the VA are among changes urologists hope to see occur in 2015.

The authors of a recent study should be commended for exploring a large national database in an attempt to understand contemporary prostate cancer screening and treatment practices.

Other products discussed in this article include a prosthesis for underactive bladder, a prostate cancer test, and an erectile dysfunction drug.

Use of bisphosphonates in men on androgen deprivation therapy (ADT) for prostate cancer remains low despite the fact that the practice is recommended in several guidelines, Canadian researchers say.

Use of primary androgen deprivation therapy in men with localized prostate cancer is associated with decreased survival compared to men who receive no active treatment, according to new research findings.

The Prolaris prostate cancer test could save the health care system $6 billion over 10 years, according to data from one of several new studies examining the economic and clinical benefits of newer biomarker-based prostate cancer assays.

Robert A. Dowling, MD examines the possible impact of prostate cancer surveillance management approaches on a urology practice’s reimbursement and income.

A receptor involved with HIV therapy also appears to be linked to prostate cancer metastases, according to recent research from Thomas Jefferson University, Philadelphia.

Long-term testosterone therapy in hypogonadal men appears to be safe and does not increase the risk of prostate cancer, according to a newly published analysis of three patient registries.

A report analyzing more than 191,000 cases of prostate cancer has found that being overweight or obese increases men’s risk for advanced prostate cancer.

Results from the U.S. validation study of a test that combines plasma levels of four prostate-specific kallikreins with clinical data demonstrated it accurately predicts high-grade prostate cancer and is superior to a validated clinical variable-based risk calculator.

Dendreon Corp., the maker of sipuleucel-T (Provenge), said it expects no impact on access to the prostate cancer immunotherapy following the company’s Chapter 11 filing last week.

This video demonstrates a wide-excision prostatectomy for patients with locally advanced, high-risk prostate cancer.

These videos depict a classic tennis racquet bladder neck reconstruction and mucosal eversion as popularized by Patrick Walsh, MD, for open prostatectomy, but used by relatively few surgeons for robotic prostatectomy.

The AUA has refuted findings from a recent study that reported a modest association between vasectomy and lethal prostate cancer.

Other products featured include a 16-slice CT scanner, new generic testosterone gel, prostate cancer risk calculator, and more.

New biomarkers for prostate cancer are showing great promise for addressing the limitations of existing diagnostic and prognostic tools, according to opinion leaders who spoke on this topic at the Large Urology Group Practice Association annual meeting in Chicago.

Magnetic resonance imaging (MRI) is a promising tool for optimizing prostate cancer biopsy that appears to overcome the shortcomings of conventional systematic transrectal ultrasound (TRUS)-guided biopsy and also provides novel information for risk stratification that can guide the decision of whether to perform biopsy, according to Samir Taneja, MD.

The American Society of Clinical Oncology has endorsed the AUA/American Society for Radiation Oncology guideline on the use of adjuvant and salvage radiotherapy after prostatectomy.

Two recently published studies provide new insight on cardiovascular morbidity and mortality associated with androgen deprivation therapy in men with prostate cancer.

Despite another anti-prostate cancer screening message (this one from north of the border), many U.S. urologists have already taken a more individualized approach to screening and will likely continue to do so.

A vast majority of top-ranked consumer health websites disagree with the U.S. Preventive Services Task Force’s recommendation against screening for prostate cancer, according to a study presented at the American College of Surgeons clinical congress in San Francisco.

The number of sexual partners a man has could be related to risk of being diagnosed with prostate cancer, Canadian researchers report.

Inflammation may be the missing link between vitamin D and prostate cancer, new study findings from the University of Colorado Cancer Center in Denver suggest.

In this article, Robert A. Dowling, MD, reviews the challenges of implementing active surveillance in a practice as well as ways to surmount these obstacles.

In separate actions, the FDA allowed the marketing of a urinary prosthesis for women and approved a supplemental new drug application for a lymphatic mapping agent.

Palmetto GBA, a Medicare Administrative Contractor that assesses molecular diagnostic technologies, has issued a draft local coverage determination for the Prolaris prostate cancer test, Myriad Genetics, Inc. announced.