How phase 3 trial data led to FDA approval of flotufolastat F 18 (Posluma) in prostate cancer
June 14th 2023“I think the importance of this is that these are more accurate than our current imaging studies in helping us to better counsel patients on the expected treatment options given their current situation,” says Brian F. Chapin, MD.
Dr. Morgans on real-world study comparing darolutamide, enzalutamide, and apalutamide in nmCRPC
June 12th 2023"We found in both unadjusted and adjusted analyses that patients seemed to discontinue enzalutamide and apalutamide at slightly earlier time points than darolutamide," said Alicia Morgans, MD.
Alleviating health care professional burnout by taking your foot off the accelerator
June 9th 2023“It's hard for us as physicians to think about anything other than continuing to put the accelerator into the red zone. But sometimes, a little bit of self-awareness can allow you to sustain a career for many years longer,” says Colin P. West, MD, PhD.
Dr. Catalona on the slow adoption of active surveillance in the United States
June 8th 2023"It pretty much has been adopted around the world so that about 80% of men who are diagnosed with low-risk prostate cancer go on active surveillance. In Sweden, it's about 80%. That's considered the goal. But the United States has been slow in adopting this," says William J. Catalona, MD.
Dr. Gupta on 4-year data for enfortumab vedotin/pembrolizumab in urothelial carcinoma
June 8th 2023Shilpa Gupta, MD, discusses long-term outcomes of the EV-103 trial, which explored the first-line combination of enfortumab vedotin and pembrolizumab in cisplatin-ineligible patients with locally advanced or metastatic urothelial carcinoma.
Dr. Siefker-Radtke on upfront erdafitinib/cetrelimab in cisplatin-ineligible urothelial cancer
June 7th 2023“Our ultimate goal is to come up with strategies that really enhance the life expectancy and the treatment options for our patients with urothelial cancer,” says Arlene O. Siefker-Radtke, MD.
Dr. Psutka on the use of acupuncture prior to BCG therapy in patients with NMIBC
June 5th 2023"All the patients said that they were pleased with the acupuncture that they received, and about 75% said that they would refer other people going through BCG to acupuncture," says Sarah P. Psutka, MD, MS.
Dr. Olmos on outcomes in first-line mCRPC based on BRCA/HRR status
June 4th 2023David Olmos, MBBS, MSc, PhD, discusses research presented at the ASCO 2023 Annual Meeting assessing outcomes with first-line novel hormonal therapy or taxane therapy in metastatic castration-resistant prostate cancer based on patients' BRCA/HRR status.
Dr. Hutson presents follow-up CLEAR study data on lenvatinib/pembrolizumab in aRCC
June 4th 2023"The overall survival, Kaplan Meier curves, are maintained with a hazard ratio of 0.79 for the intent-to-treat patient population of lenvatinib/pembrolizumab versus sunitinib," said Thomas E. Hutson, DO, PharmD, FACP.
Dr. Stifelman on retroperineal partial nephrectomy for anterior vs posterior renal tumors
May 30th 2023"Even though most urologists who do retroperitoneal surgery do it for posterior tumors, you actually can do it equally well with as equally good success for an anterior tumor," says Michael D. Stifelman, MD.
Investigators identify link between food insecurity and urge urinary incontinence
May 30th 2023"Our main finding was that participants who experienced food insecurity in the past year were at 55% increased odds of reporting at least 1 episode of urge urinary incontinence in the past month, compared with those who have not experienced food insecurity," says Joseph Kim, MD.
Dr. Rubin on the importance of vaginal hormone treatments for women over 45
May 29th 2023“The take-home message is that as a practicing urologist, you should be treating genitourinary syndrome of menopause and giving any woman over 45 vaginal hormones, whether in the form of vaginal estrogen or vaginal DHEA,” says Rachel S. Rubin, MD.