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Madrid, Spain-Botulinum-A toxin shows positive results as an alternativetreatment of neurogenic detrusor overactivity when oral therapies or intravesicalanticholinergics fail or are intolerable, according to results of four separatestudies presented at the European Association of Urology 18th congress here.The agent, although FDA-approved for the treatment of skin wrinkles andrelated indications, is not approved for detrusor overactivity but has beenused by some U.S. and European urologists for this indication.