Opinion

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Defining mCSPC: Diagnostic Criteria, Imaging Approaches, and Patient Identification

Key Takeaways

  • mCSPC and mHSPC refer to prostate cancer with metastases that remain responsive to hormone therapy, often used interchangeably.
  • Both conditions involve the presence of metastases and sensitivity to androgen deprivation therapy (ADT).
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Panelists discuss how metastatic castration-sensitive prostate cancer (mCSPC) is defined by its sensitivity to androgen deprivation therapy, while metastatic hormone-sensitive prostate cancer (mHSPC) emphasizes the cancer’s responsiveness to hormone treatment, highlighting the nuanced differences in patient management strategies.

Video content above is prompted by the following:

How do you define mCSPC and mHSPC? How are they different? (Lowrance et al. AUA/SUO Guideline, 2023) (NCCN, Prostate Cancer, v4.2024)

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