The Heterogeneity of Prostate Cancer

Experts on prostate cancer discuss the heterogeneity of the disease and the rationale for using medications with different mechanisms of action, including androgen deprivation therapy.

EP: 1.Prostate Cancer Treatment: The Evolving Therapeutic Landscape

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EP: 2.The Heterogeneity of Prostate Cancer

EP: 3.The Role of ADT in Localized or Locally Advanced Prostate Cancer

EP: 4.EMBARK Study: ADT in Nonmetastatic Castration-Sensitive Prostate Cancer

EP: 5.Treatment Considerations in Nonmetastatic CSPC

EP: 6.Combination Therapies and Intensifications of ADT in Advanced Prostate Cancer

EP: 7.Treatment Options in Castration-Resistant Prostate Cancer

EP: 8.The Relationship Between Prostate Cancer and Cardiovascular Disease

EP: 9.Impact of GnRH Agonists and Antagonists on Cardiovascular Outcomes in Prostate Cancer

EP: 10.ADT Treatment Considerations and Unmet Needs in Prostate Cancer

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In this podcast episode, Adam B. Murphy, MD, MBA, MSCI, discusses the need to increase diversity in clinical trials, specifically focusing on studies in prostate cancer.

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"Efficacy outcomes with darolutamide plus ADT were improved vs placebo plus ADT regardless of disease volume," said Fred Saad, MD, FRCS.

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Zeyad Schwen, MD, a urologic oncologist at Cleveland Clinic, discusses how patient factors and cancer characteristics are key to deciding between focal therapies and whole gland treatment for prostate cancer.

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"Patients with metastatic hormone-sensitive prostate cancer benefited from treatment with darolutamide plus ADT and docetaxel regardless of age," said Joan Carles, MD, PhD.

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