ADT as the Backbone for Combination Treatments in Advanced Prostate Cancer

A focused discussion on how ADT is used as the backbone of prostate cancer therapy across different prostate cancer risk groups and according to metastatic and castration sensitivity status.

EP: 1.How PSA Has Impacted the Use of ADT in Prostate Cancer

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EP: 2.ADT as the Backbone for Combination Treatments in Advanced Prostate Cancer

EP: 3.Understanding and Mitigating the Cardiometabolic Risks of ADT

EP: 4.Should Men with Prior CVD be Treated Preferentially with a GnRH Antagonist?

January 2023 AbbVie Inc. Company Confidential

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Benjamin P. Saylor

Median PFS was 35 months in the MDT plus SOC group vs 21 months in the SOC alone group.

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Dr. Murphy on increasing diversity in cancer clinical trials

Urology Times staff

In this podcast episode, Adam B. Murphy, MD, MBA, MSCI, discusses the need to increase diversity in clinical trials, specifically focusing on studies in prostate cancer.

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Darolutamide plus ADT shows mHSPC benefit regardless of disease volume

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"Efficacy outcomes with darolutamide plus ADT were improved vs placebo plus ADT regardless of disease volume," said Fred Saad, MD, FRCS.

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Zeyad Schwen, MD, a urologic oncologist at Cleveland Clinic, discusses how patient factors and cancer characteristics are key to deciding between focal therapies and whole gland treatment for prostate cancer.

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"Patients with metastatic hormone-sensitive prostate cancer benefited from treatment with darolutamide plus ADT and docetaxel regardless of age," said Joan Carles, MD, PhD.

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In both racial cohorts, median MFS was not reached in the darolutamide group.