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Case-Based Peer Perspectives: A 65-Year-Old Man Diagnosed with PSMA-positive mCRPC

Advancing Prostate Cancer Treatment With Lutetium 617 and PSMA PET Imaging

Videos

Neal Shore, MD, FACS discusses how a 65-year-old man with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) underwent a treatment journey that included androgen deprivation therapy, docetaxel, cabazitaxel, and enzalutamide before ultimately being evaluated for Lutetium-177 therapy based on PSMA PET imaging and trial data.

Neal Shore, MD, FACS, discusses the progress of a 65-year-old patient with  mCRPC through various treatments and evaluation for Lutetium-177 therapy based on his PSMA PET scan and MRI.

Patient Case 1: A Sixty-Five-Year-Old Man With Prostate Cancer

Neal Shore, MD, FACS, discusses how the patient profile in the VISION trial, which involved progression on multiple therapies, reflects typical cases for Lutetium-177 treatment, emphasizing the crucial role of PSMA PET imaging in determining treatment suitability.

PSMA PET Imaging and Radioligand Therapy in mCRPC: Insights From VISION and TheraP Trials

Neal Shore, MD, FACS, emphasizes the significance of the VISION and TheraP trials in supporting the FDA approval of Lutetium-177 for patients with mCRPC who have undergone androgen receptor inhibitor and taxane treatments, highlighting the role of PSMA PET imaging in treatment sequencing and patient selection.

Sequencing Treatment and Optimizing Care in mCRPC: Insights From VISION and TheraP Trials

Neal Shore, MD, FACS, discusses the evolving use of follow-up PSMA PET scans and the recent FORE trial, which showed that Lutetium-177 improves radiographic progression-free survival and PSA levels in prechemotherapy patients with mCRPC, with more data on overall survival and quality of life expected.

Neal Shore, MD, FACS, highlights the exciting advancements in radioligand therapy for prostate cancer, noting that ongoing trials are exploring its use in various disease stages and settings, and emphasizes the importance of reviewing the VISION and FORE trial publications for further insights.

Treatment Considerations for PSMA-Positive mCRPC Patients

Case Based Peer Perspectives

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Advancing Prostate Cancer Treatment With Lutetium 617 and PSMA PET Imaging

EP: 1.Patient Case 1: A Sixty-Five-Year-Old Man With Prostate Cancer

EP: 2.PSMA PET Imaging and Radioligand Therapy in mCRPC: Insights From VISION and TheraP Trials

EP: 3.Sequencing Treatment and Optimizing Care in mCRPC: Insights From VISION and TheraP Trials

EP: 4.Advancing Prostate Cancer Treatment With Lutetium 617 and PSMA PET Imaging

EP: 5.Treatment Considerations for PSMA-Positive mCRPC Patients