Prostate Cancer

ARN-509, a novel oral antiandrogen, was safe, well tolerated, and showed promising efficacy in men with high-risk, non-metastatic castration-resistant prostate cancer (CRPC) in a phase II study, reported Neal D. Shore, MD.

Higher radiation doses don’t confer a survival benefit in men with low-risk prostate cancer, although they do increase survival rates for men with medium- and high-risk cancers, the authors of a new study report.

Despite the strategy’s benefits, many low-risk patients still undergo surgical or radiation treatment, researchers report.

Study findings suggest that high levels of vitamin D could be harmful to the prostate.

With several years now passing since the USPSTF issued its grade D recommendation discouraging PSA-based prostate cancer screening, researchers are reporting conflicting findings on its impact on clinical practice.

We are entering a new era when patients will present not with an elevated PSA but rather with symptoms, writes Henry Rosevear, MD.

Urology Times’ “Best of AUA 2015” report provides a guide to the meeting’s take-home messages in 15 therapeutic areas-an information-packed, condensed summary of the top papers and presentations.

Active surveillance for men with low-risk prostate cancer has made it to prime time. That was the message of Stacy Loeb, MD, who moderated a press conference at the AUA annual meeting, where four studies documented the increasing popularity and safety of active surveillance in managing low-risk disease.

Chemicals in green tea may help inhibit development of prostate cancer in men at high risk, according to results of a randomized, controlled trial.

An experimental assay could reduce the need for prostate needle biopsies, researchers say.

In a phase III study, a drug that blocks production of a protein was associated with a 27% reduction in the risk of death.

A study of patient outcomes 1 year after localized prostate cancer care seems to indicate that the answer is “no.”

Despite the benefit shown in this research, a study author says it’s too early to change practice.

A novel compound used with positron emission tomography imaging can identify foci of prostate cancer not found on biopsy of the prostate pre surgery or on the post-surgery specimen, according to a pilot study presented at the American Association of Cancer Research annual meeting in Philadelphia.

A large prospective study suggests men with male pattern baldness (MPB), particularly moderate MPB, are more likely to die from prostate cancer, compared to men with no MPB.

In this article, Robert A. Dowling, MD, examines some of the practice-related implications of the rapid change in the management of patients with advanced prostate cancer.

Other products featured include: Radiosurgery collimator allows treatment of broad rang of tumors and Phi prostate cancer test and more.

Panelists and audience members at the recent AUA “crossfire” debate on focal therapy show why the treatment is so controversial.

The cell surface amino acid glypican-1 (GPC-1) represents a potential new biomarker for prostate cancer, said Jonathan Henderson, MD, at the AUA annual meeting.

A novel metric for evaluating post-prostatectomy outcomes could support quality improvement initiatives for optimizing patient recovery.

Recently published research on a novel chemotherapy-immunotherapy combination is “exciting for multiple reasons,” says one expert.

A new study assesses how a biopsy-based gene test impacts prostate cancer treatment recommendations in three high-volume practices.

Products in the pipeline for prostate cancer, bladder cancer, and much more.

Post-radical prostatectomy radiation therapy in patients at risk of prostate cancer recurrence is on the wane in the U.S., despite evidence and guidelines supporting the practice, recently published research indicates.

Biomarker models to predict disease progression in prostate cancer have a promising future, but at present, they have not fully justified their claimed clinical utilities, according to the authors of an independent review and analysis of the literature.

Other products featured include a spacer system to protect men undergoing PCa radiotherapy, a pelvic floor exercise app, and more.

I am more optimistic that we will find a way to treat those who truly need to be treated and follow those unlikely to die from their disease.

Placement of a nerve “wrap” around the neurovascular bundle during nerve-sparing robot-assisted radical prostatectomy appears to accelerate the early restoration of continence and potency following surgery, a recently published study has shown.

Products in the pipeline for prostate cancer, bladder cancer, stress urinary incontinence, chronic prostatitis/chronic pelvic pain syndrome, hypoactive sexual desire disorder.

To help you maximize your AUA experience, Urology Times’ editorial board and other thought leaders have pored over hundreds of abstracts to identify the key trends and can’t-miss research from this year’s meeting.