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Exploring PD-1/PD-L1 Pathways and Innovative Treatments for NMIBC

Key Takeaways

  • PD-1/PD-L1 pathways are pivotal in cancer immunotherapy, enabling tumor immune evasion by inactivating T-cells through receptor-ligand interactions.
  • Investigational agents in BCG-naive and unresponsive settings include gene therapy and intravesical treatments, targeting enhanced immune activation.
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Video content above is prompted by the following:

  • What is the role of the PD-1/PD-L1 pathways in cancer immunotherapy?
  • What are their mechanisms of action?

What agents are being investigated in the BCG-naive and unresponsive setting? Gene therapy, intravesical?

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