Opinion

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Innovations in NMIBC Treatment: The Synergy of BCG and PD-1/PD-L1 Inhibitors

Key Takeaways

  • Combining BCG and PD-1/PD-L1 inhibitors may enhance antitumor activity through complementary mechanisms, potentially improving outcomes in NMIBC.
  • BCG stimulates immune response, while PD-1/PD-L1 inhibitors prevent immune evasion, providing a rationale for their combined use.
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Video content above is prompted by the following:

  • How might the combination of BCG and PD-1/PD-L1 inhibitors affect antitumor activity compared with using each agent alone?
  • What is the rationale for using these therapies in combination?
  • How do you think the combination therapies will evolve treatment of non–muscle-invasive bladder cancer (NMIBC)?
  • How would the use of PD-1/PD-L1 inhibitors plus BCG in high-risk NMIBC impact patient flow in urology practice?

THE SPEAKER WILL HIGHLIGHT THE IMPORTANCE OF A MULTIDISCIPLINARY APPROACH

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