Standard of Care in NMIBC

Panelists discuss how low-risk non–muscle-invasive bladder cancer (NMIBC) requires transurethral resection of bladder tumor (TURBT) with surveillance. Intermediate-risk disease needs adjuvant intravesical chemotherapy. High-risk cases receive BCG induction/maintenance therapy after TURBT, with close monitoring.

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EP: 1.Standard of Care in NMIBC

EP: 2.BCG-Unresponsive NMIBC and Treatments

EP: 3.Recent FDA Approvals in NMIBC

EP: 4.Selecting Treatment for BCG-Unresponsive NMIBC

EP: 5.BOND-003 Trial and Cretostimogene for Treatment of NMIBC

EP: 6.Other Emerging Intravesical Therapies in NMIBC

EP: 7.Emerging Immunotherapies in NMIBC

EP: 8.Future of BCG in NMIBC

Video content above is prompted by the following:

• Discuss the current standard of care for patients with low-risk, intermediate-risk, and high-risk NMIBC? What is the role of BCG in these patients?

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Neoadjuvant APL-1202 plus tislelizumab is safe in patients with MIBC

Hannah Clarke

The pCR rate was 33% with APL-1202 plus tislelizumab compared with 26% with tislelizumab alone.

January 14th 2025

Episode 2 Podcast: Managing Overactive Bladder: From Dual Diagnoses to Geriatric Challenges

Wayne Kuang, MD Steven Maislos, MD

Panelists discuss how managing overactive bladder in older adults requires a holistic approach that integrates treatment of comorbidities, emerging therapeutic options, and quality-of-life considerations to optimize patient outcomes.

February 18th 2025

RETAIN-2 interim data promising for dose-dense MVAC plus nivolumab in MIBC

Benjamin P. Saylor

“Among active surveillance patients, 82% are metastases free, and 60% were metastases free and had an intact, un-radiated bladder,” said Pooja Ghatalia, MD.

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Episode 1 Podcast: Understanding Overactive Bladder (OAB): Pathophysiology, Diagnosis, and Management in Older Adults

Wayne Kuang, MD Bilal Chughtai, MD

Experts discuss overactive bladder and the impacts on quality of life, distinguishing OAB from BPH, and how a delayed diagnosis can worsen symptoms.

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Benjamin P. Saylor

"The results [indicate] that neoadjuvant DV combined with toripalimab had promising efficacy and acceptable safety in patients with HER2-expressing MIBC,” said Xinan Sheng, MD.

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The pCR was 37.3% (95% CI, 33.2-41.6) in the durvalumab arm and 27.5% (95% CI, 23.8-31.6) in the comparator arm.