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Overview of BCG-Unresponsive NMIBC

Key Takeaways

  • BCG-unresponsive NMIBC is defined by persistent or recurrent high-grade tumors or carcinoma in situ after adequate BCG therapy.
  • This condition requires alternative therapeutic strategies or radical cystectomy due to the failure of BCG treatment.
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Katie S. Murray, DO, provides an overview of BCG-unresponsive non–muscle-invasive bladder cancer (NMIBC), defining it as a form of bladder cancer that does not respond to BCG therapy and explaining how it differs from BCG-responsive NMIBC in terms of treatment outcomes and disease progression.

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      1. Would you please start by giving a brief overview of BCG-unresponsive NMIBC?
      • What defines this condition?
      • How does it differ from NMIBC that responds to BCG treatment?

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