BCG-unresponsive NMIBC is defined by persistent or recurrent high-grade tumors or carcinoma in situ after adequate BCG therapy.
This condition requires alternative therapeutic strategies or radical cystectomy due to the failure of BCG treatment.
BCG-responsive NMIBC achieves and maintains a complete response following BCG therapy, contrasting with the unresponsive form.
SHOW MORE
Katie S. Murray, DO, provides an overview of BCG-unresponsive non–muscle-invasive bladder cancer (NMIBC), defining it as a form of bladder cancer that does not respond to BCG therapy and explaining how it differs from BCG-responsive NMIBC in terms of treatment outcomes and disease progression.